Ensure that your child is protected and healthy.
Third Generation IVF
The latest technology in In Vitro Fertilization
Peace of Mind
Protects Your Family
Prevents the transmission of hidden genetic diseases in your family’s lineage.
Reduced Miscarriage Risk
Prevents poor fetal development which decreases the risk of pre-mature termination.
Improved Success
Increases the success rate of embryo transfer and reduces pregnancy failures.
Tap to Reveal.
What is it?
IVF+PGT
Third-generation IVF is the latest in IVF in technology.
Firstly, it is still an IVF process, meaning that the male sperm and the female egg are combined outside of the human body to create an embryo. However, before the embryo is implanted in the uterus of a woman, there is an additional step. The embryo’s genetic material (DNA) is tested or screened; Preimplantation Genetic Testing (PGT) or Preimplantation Genetic Screening (PGS).
After genetic testing/screening, only the genetically acceptable embryos are selected for uterine implantation.
What can it do?
Healthier Children
Third-generation IVF is developed to reduce genetic diseases.
The technology involves screening the DNA of embryos for chromosomal abnormalities, which are errors in the genetic code. These errors can cause over 300 different genetic diseases such as cystic fibrosis, Down syndrome, Turner syndrome, Williams syndrome, Huntington’s disease and many more. Unfortunately, these types are diseases are regarded as uncurable. Genetic abnormalities also lead to increased rates of miscarriage.
3rd gen. IVF provides a solution that prevents these diseases, leading to healthier children with a better quality of life.
The Best in Preventive Care
Provide your child with the best quality of life.
Effective
Over 300 different types of diseases screened.
Be Reassured
Be worry-free knowing that your child would grow-up healthy and strong.
Contact us
Speak to our friendly customer service team to find out more.
IVF Treatment Process Flow
Below we explain the general process for BabySun Fertility Center 3rd generation IVF treatments. This is performed after both the egg and sperm donation process and is simplified into four main steps; 1. Sperm Capacitation, 2. Fertilization, 3. Culture and 4. Testing and Screening.
Sperm Capacitation
The main purpose of this process is to modify the structure of the sperm so that it is prepared for egg fertilization. In natural reproduction, as the sperm swims through the uterus towards the fallopian tubes, they undergo a series of physical transformations.
Under in vitro laboratory conditions, these transformations need to be induced as the sperm is directly transported to the egg.
The secondary purpose is isolate the healthiest of sperm from the semen mixture for IVF. Low-motility sperm, dead cells and seminal plasma are separated out, leaving behind quality sperm concentrate.
Fertilization
The fertilization method of choice is Intracytoplasmic sperm injection, ICSI. ICSI involves selecting a single, high-quality sperm and directly injecting the sperm cell into an egg via a fine needle. This method of fertilization is renowned for its high success rates when compared to classical 1st generation IVF; which is where sperm is placed outside of an egg cell and the sperm is required to insert itself through the egg coating.
ICSI overcomes many male-factor infertility cases, such as low sperm count, poor/abnormal sperm motility and abnormal sperm morphology (physical shape). It also overcomes cases where the female egg has a thickened outer coating, a thickened zona pellucida, which results in sperm being unable to penetrate into the egg.
The combination of ICSI and IVF alone is commonly regarded as 2nd generation IVF.
Culture
Culturing involves maturing the newly fertilized embryo in the lab. The primary goal of culturing embryos into blastocysts is to improve embryo transfer success rate, when compared to early transfer.
The process involves placing the new embryo into a nutrient-rich medium and incubating. This causes the cell/s in the embryo to divide and develop. Generally, 5 days after the creation of the embryo, the embryo would have developed into a blastocyst; characterized by a sphere of outer-cells (will form the placenta) and a cluster of cells inside, inner cell mass (will form the fetus).
Testing and Screening
Embryos are then graded based on morphology, physical appearance. This assessment strongly correlates to success rate when implanted. Grading results in one numerical number and two letters. The number refers to embryo development stage (1-6), the first letter refers to the quality of the inner cell mass, and the second letter refers to the quality of the trophectoderm, outer surrounding cells. The letter A refers to the highest quality, followed by grades B and C. It is generally regarded that grades 4AA, 5AA and 6AA have the highest probability of implantation success.
For 3rd generation IVF, embryos that have developed into the blastocyst stage can then progress to genetic screening. A small number of cells are retrieved from the outer trophectoderm and genetically tested/screened for abnormalities.
From these assessments, embryos of poor quality are removed from progression and only the best are used for implantation.
3rd Generation IVF Diagram
